Alexis Amore was born in Lima Peru in 1978. Along with her parents, Alexis moved to Redondo Beach, California when she was nine years old. She attended a Christian high school in Hermosa Beach, and she was a cheerleader during her time there. At fifteen, she began her modeling career as a model for Nordstrom and was featured in their fliers and publications. She continued modeling for catalogs. She had a breast augmentation prior to beginning her pornographic career.

Around 1998, during an audition for an HBO production, the person auditioning her suggested that she audition for Playboy, where she became a model for Playboy TV. While working on Playboy's Nightcalls, she interviewed Jewel De'Nyle and Alexa Rae about the pornographic industry. Comforted by their replies and wanting to experience it for herself, she contacted Vivid Entertainment and was hired for her first film (The Watcher 6) two days later in November 1999 as one of her first seven porn videos.

In January 2003, Alexis re-entered the industry after a short break. Not only did Alexis continue to perform, she has also begun directing. Her first movie as director was Lascivious Latinas.

Since early 2006, Amore has infrequently written for AVN Insider and has also launched a new sex-toys contract with California Exotic Novelties.